BREAKTHROUGHIST

Brain-Computer Interfaces

Reading and writing to the brain — from clinical motor restoration to consumer neural input.

19 companies · 5 segments

Invasive BCI — Implanted Electrodes

Neuralink

N1 chip with 1,024 threads; 5+ humans implanted

Synchron

Stentrode via blood vessels (no craniotomy)

Paradromics

High-bandwidth implant; first human June 2025

Neuromodulation & Stimulation

Nevro

Chronic pain spinal stimulation

Non-Invasive — Consumer & Clinical EEG

Neurable

Everyday brain-sensing headphones

Kernel

Time-domain functional NIRS helmet

Openwater

Optical brain imaging & therapeutics

Functional Imaging & Decoding

Neurotherapeutics & Biotech Adjacent